Jacob Barlow

Senior Associate

2024 - Current

Senior Associate, Life Sciences Research

2023

Associate, Life Sciences Research

2021 - 2023

Graduate Student

2017 - 2021

Bioengineering PhD program: Developed quantitative sequencing methodologies and data analysis techniques to enhance microbiome based discoveries and clinical translation. Worked on preclinical and clinical applications connected to the oral, small-intestinal, and large-intestinal microbiome with specific work on small-intestinal bacterial overgrowth (SIBO), Inflammatory bowel disease (IBD), Primary sclerosing cholangitis (PSC), Celiac Disease, and the gut-brain axis.

Fellow

2021 - 2021

Accepted to 2021 Summer Fellows Program. Active member of the tools/diagnostics team. Supported sourcing and diligence and engaged with portfolio companies. Completed individual projects on emerging diagnostic areas.

Engineering Co-op

2016 - 2017

Oral drug delivery R&D from formulation design to in-vivo studies. Generated novel capsule and pill formulations of peptide drugs. Evaluated formulation designs in pig models.

Research Assistant

2013 - 2017

Worked with microfluidic droplet technology to form solid shell polymersomes for encapsulation of bacterial cells

Research Assistant

2012 - 2013

Coded estimation methods for transport properties of combustion reactions in python for the software RMG in Professor Richard West's Lab.

Bioinformatics Co-op

2015 - 2015

Designed high throughput RNA sequencing methodology from sample prep to sequence analysis. Automated sequence identification and analysis from mixed samples through python scripts.

Research Assistant

2014 - 2015

Worked with phage display to discover cancer target specific peptides to be used with PET imaging. Grew and injected tumor cells into mice for bio-distribution studies. Progressed software used alongside an endoscopy to improve detection rates.

Laboratory Technician

2013 - 2013

Performed enzymatic digestion studies to determine effect of sonication on chemical kinetics. Utilized LC-MS to quantitate protein digestions.

Programmer

2012 - 2012

Converted raw mass spectrometry output files into summary reports to send back to companies. Also created an inventory and reagent database including barcode searches. Used Excel VBA.