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Jake Simson

Partner at RA Capital Management

Cambridge, Massachusetts

Overview 

Jake Simson is a Partner at RA Capital Management, L.P. with a background in biomaterials, stem cells, and tissue engineering, holding a PhD from The Johns Hopkins University. He has invested in numerous successful companies at various stages, including Outpace Bio, AltruBio, Asher Bio, and Bicara Therapeutics, among others. With a strong track record in investing in the biotech sector, Jake Simson has played a key role in funding companies like Convergent Therapeutics and Cedilla Therapeutics, showcasing his expertise in the field and contributing to the success of RA Capital Management, L.P.

Work Experience 

  • Partner

    2020 - Current

RA Capital Management is an investment advisor specializing in the life-sciences and drug development sectors.

  • Principal

    2017 - 2020

  • Analyst

    2015 - 2017

  • Associate

    2013 - 2015

RA Capital Management is an investment advisor specializing in the life-sciences and drug development sectors.

  • PhD Candidate

    2008 - 2013

    - Developed and optimized a novel biological adhesive hydrogel for meniscal and cartilage tissue repair - Evaluated the potential of biologic hydrogels to regenerate bone and cartilage in a pre-clinical large animal model as a critical step to seeking funding for clinical translation - Collaborated with clinicians to develop endoscopic delivery protocol of a tissue adhesive to prevent scarring in gastroenterological and otolaryngological applications - Mentored seven undergraduate or visiting students in biomaterial development and regenerative medicine techniques

  • Collaborating Researcher

    2010 - 2010

    Developed a fully biologic hydrogel carrier to deliver and localize recombinant human bone morphogenetic protein-2 to enhance musculoskeletal tissue repair

Pfizer is a biopharmaceutical company that provides affordable access to safe, effective medicines and health care services.

Raised $32,000,000,000.00 from Starboard Value.

  • Visiting Research Associate

    2009 - 2009

    Provided technical support for data collection and analysis leading to approval of ChondroCelect®, the first cell therapy approved by the European Medicines Agency

  • Undergraduate Research Associate

    2006 - 2008

    - Identified and analyzed the distribution of lubricin in samples of human intervertebral disc using immunohistochemistry techniques to determine the source and role of this protein in disc function - Synthesized and characterized collagen-GAG hybrid scaffolds for use in nucleus pulposus regeneration using human mesenchymal stem cells

Articles About Jake

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