JO

James Orsillo

General Partner at Underscore VC

Greater Boston

Overview 

James Orsillo is a General Partner and CFO/O at Underscore VC in Greater Boston, with a background in finance, strategic planning, and corporate leadership. He has served as Chief Financial Officer for successful companies like Maxwell Health and Evariant, and holds a Charterholder designation from the CFA Institute. Orsillo's career highlights include his roles as a Board Director for companies like Salsify and TetraScience, as well as his expertise in financial analysis, forecasting, and strategic financial planning.

Work Experience 

  • Board Director

    2024 - Current

Salsify helps brands by providing tools to track and analyze inventories, presentation, and sales of goods on digital shelves.

Raised $452,600,000.00 from CrossWork.us.

  • Board Director

    2023

  • Board Director

    2023

CloudZero is a SaaS platform that automates the collection, allocation, and analysis of cloud cost data to reveal opportunities for savings.

Raised $63,125,000.00 from Innovius Capital, Matrix, G20 Ventures, Threshold and Underscore VC.

  • Advisory Council Member

    2023

  • Board Director

    2021

TetraScience is an R&D cloud data management company that empowers transformation in life sciences and drug discovery.

Raised $99,145,000.00 from Alkeon Capital and Insight Partners.

  • General Partner, CFO/O

    2021

  • CFO/O

    2018 - 2021

  • Advisory Board Member

    2016

OPEXEngine is the leading performance benchmarking solution for SaaS and software companies, acquired by Bain & Company in 2021.

  • Chief Financial Officer

    2016 - 2018

  • Chief Financial Officer

    2012 - 2016

  • Senior Manager, Corporate FP&A

    2010 - 2011

American Tower is a real estate investment trust that provides the infrastructure for modern digital communications.

Raised $6,536,400,000.00.

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