JG

John Glasspool

Biopharmaceutical Leader

Boston, Massachusetts

Overview

Work Experience

  • Member of the Board Emerging Companies Section Governing Board

    2022 - Current

  • Venture Partner

    2018

    Agent Capital is a healthcare venture capital firm focused on investing in novel, differentiated therapeutics and treatments that address unmet patient needs.

  • Board Member

    2019

    Relmada (Nasdaq: $RLMD) is a clinical-stage company developing novel therapies for the treatment of CNS diseases.

  • Senior Advisor

    2016

    Advisor/Contributor on key initiatives, including financing/reimbursement models, policy recommendations for durable therapies, and Efficacy to Effectiveness (E2E) strategies.

  • CEO and President

    2019 - 2024

    Anthos Therapeutics is a clinical-stage biopharmaceutical company developing innovative therapies for high-risk cardiovascular patients. The company’s lead program is abelacimab (MAA868), an antibody exhibiting dual inhibition of coagulation Factor XI and its activated form XIa. Early clinical trials indicate abelacimab has the potential to attenuate pathological thrombosis with minimal impact on hemostasis, thereby preventing or treating a variety of thrombotic disorders with lowered bleeding risk. Abelacimab’s anticipated monthly dosing combined with the potential for greater effectiveness and lowered bleeding profile are expected to provide major advantages over existing standards of care and allow greater numbers of people to be treated.

  • Board Member

    2017 - 2023

    DalCor is pioneering precision medicine for cardiovascular disease. The company is developing dalcetrapib, a unique cholesterol ester transfer protein (CETP) inhibitor, as a potential targeted treatment to address the residual cardiovascular risk in patients carrying a specific ADCY9 genetic profile to maximize clinical benefit.

  • Consultant

    2017 - 2018

    Consulting to Roivant on commercial go-to-market activities, including operating, launch, and access plans.

  • EVP, Head of Corporate Strategy and Customer Operations

    2015 - 2017

    Member of Executive Team that led Baxalta through spin-off from Baxter Healthcare and subsequent merger agreement with Shire to form a Top 20 biopharma company. Championed external product development model and led Baxalta Ventures and Vitesse Biologics, along with more traditional business development and licensing and M&A, to create a conduit between innovation and commercialization.

  • VP, Head of Emerging Therapies and Market Development, Bioscience

    2012 - 2015

    Built oncology franchise from the ground up with three in-licenses agreements and development of an internal commercial team. Architect of commercial infrastructure for $12 billion business built around the changing needs of multiple stakeholders – patients, physicians, providers, payers, and policymakers (P5) – establishing a comprehensive approach to the successful launch of new drugs.

  • Head Region Europe - Vaccines & Diagnostic

    2009 - 2012

    Member of Executive Committee for division. Region head with revenue of more than $500 million and 275 people. Prepared for the commercial introduction of the first vaccine for meningitis B, including national recommendations. Collaborated with German health authorities to ensure competition in TBE vaccines after introduction of the AMNOG process. Partnered with DG Sanco on joint procurement agreements for European Union for potential pandemic threats.

  • Global Head Pharma Commercial Operations, Pricing and Market Access

    2008 - 2009

    Responsible for all Pharma product value proposition and process unit in global marketing and sales, analytics, and market research. Strengthened access process through introduction of iMAP (integrated market access plan) and risk-sharing schemes.

  • Head of Cardiovascular & Metabolism Franchise

    2004 - 2008

    Managed products from proof-of-concept to loss-of-exclusivity for business with sales of $6+ billion and 50 people. Grew CVM franchise sales from $4.9 billion to $6.7 billion over a three-year period. Managed multiple product launches.

  • Head of Neuroscience Franchise

    2003 - 2004

    Managed all stages of development for neuroscience products. Created study program and gained approval for first treatment for Parkinson’s dementia, despite FDA not initially accepting condition as a unique form of dementia.

  • Head of Marketing NS

    2002 - 2003

  • Head of Marketing Neurology

    2002 - 2003

    Managed global marketing and sales for broad neurology portfolio, including epilepsy, Alzheimer’s, and Parkinson’s.

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