JS

Joseph Siletto

Growth Capital and Private Equity Investor

Needham, Massachusetts

Overview 

Joseph Siletto is a Growth Capital and Private Equity Investor based in Needham, Massachusetts, with a strong background in board-level positions and expertise in venture capital, mergers & acquisitions, and valuation. Notable highlights of his career include serving as Managing Director at Vivo Capital and making investments in companies like INBRACE and Sera Prognostics. Currently, Joseph Siletto holds board-level positions in various companies and has a track record of successful investments, including in Aerobiotix and Preventice Solutions.

Work Experience 

  • Board Member

    2024 - Current

    Clinical stage biotech company focused on renal disease

Pathalys is a clinical biopharmaceutical company that develops therapeutics that improve late-stage chronic kidney disease.

Raised $266,000,000.00 from J.P. Morgan Asset Management, KB Investment, Japan Post Investment, Samsara BioCapital, TCG Crossover, DaVita Venture Group, Marshall Wace and Catalys Pacific.

  • Managing Partner

    2024

    Co-head of JP Morgan’s new growth investing effort in healthcare.

J.P. Morgan Ventures Energy Corporation provides commodity risk management solutions in both the physical .

  • Board Member

    2021

    Led $50 million growth equity investment into a founder-controlled neurovascular medical device company. Worked with founder to purchase a new 85,000 square foot manufacturing facility and negotiated a sale-leaseback transaction to generate a significant gain on the sale, sourced a first time credit facility and helped with the recruitment of the commercial team. Revenue grew 10x in 1st three years post investment. Employees grew from less than 100 to over 250.

  • Board Member

    2021

    Led minority equity investment in founder controlled business focused on infection prevention and staff safety

  • Interim Chief Executive Officer

    2023 - 2024

    Recapitalized existing portfolio company focused on infection prevention and surgical staff safety solutions. Restructured the company, turned the company profitable for the first time and created and implemented a new strategic plan focused on profitable growth.

  • Owner

    1988

    150+ acres of organic vineyards producing unique varietals

  • Managing Director

    2017 - 2024

    Leading healthcare-focused private capital firm with headquarters in Palo Alto, CA and offices in Shanghai and Beijing, China. Founded in 1996 with over US$6.5 Billion in assets under management. The firm invests across a wide range of sub segments of healthcare including but not limited to specialty pharmaceuticals, biotech, medical devices and services. Focus on commercial stage growth equity and controlling stake private equity investments. Source deals, negotiate and structure transactions and take active board roles on behalf of the firm.

Vivo is a global investment firm focused on healthcare with approximately $5.8 billion in AUM

  • Board Member

    2021 - 2024

  • Interim Chief Executive Officer

    2022 - 2022

    Moved from board of directors to interim CEO role to oversee the transition from a founder run business in the tech-enabled digital pathology lab space. Managed the company, hired a recruiter and brought on an outside CEO and transitioned back to a board position.

HistoWiz provides automated histopathology for biomedical researchers.

Raised $36,765,000.00 from Vivo Capital, Asahi Kasei and venBio Partners.

  • Board Observer

    2021 - 2024

    Medical device manufacturer with an innovative robotic solution for dental implant procedures.

  • Board Member

    2021 - 2024

    Highly profitable pharma services company with a specialization in solving solubility issues for pharma and biotech customers.

Serán Bioscience is a contract development and manufacturing organization.

Raised $200,000,000.00 from Bain Capital Life Sciences and Vivo Capital.

  • Co-Founder/Angel Investor

    2015 - 2024

    Revenue stage, FDA-approved gynecology-focused medical device for minimally invasive removal of uterine polyps. Designed for both office-based and OR-based surgery with no capital equipment investment needed.

Articles About Joseph

Relevant Websites