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Leshika Samarasinghe

General Partner at Twine Ventures

San Francisco, California

Overview 

Leshika Samarasinghe is the Founder & General Partner at Twine Ventures, with a background at Google and ARPA-E. She specializes in venture capital, strategy, investments, and commercialization, focusing on sectors like cleantech and lifesciences. With an MBA from Harvard Business School and a BA from Stanford University, Leshika has successfully invested in a variety of start-ups, demonstrating expertise in supporting female and diverse founders in the San Francisco Bay Area.

Work Experience 

  • Founder & General Partner

    2021 - Current

    Twine Ventures is an early stage venture capital firm partnering with mission-driven founders improving human health, climate, and financial empowerment.

Twine Ventures is an early-stage venture capital firm that focuses on human health, climate, and financial empowerment.

  • Investor

    2023

Alchemy creates and implements clinical pharmacy programs and deploys technology products that use the pharmacy.

Raised $31,000,000.00 from Sandberg Bernthal Venture Partners, AlleyCorp, Springbank Collective, Twine Ventures, Andreessen Horowitz, Magic Johnson Enterprises, Banc of California and Sheryl Sandberg.

  • Investor

    2023

  • Investor

    2022

curing disease with novel spatial and functional biology tools

  • Investor

    2021

Waymark is a company dedicated to improving access and quality of care for people receiving Medicaid.

Raised $107,000,000.00 from New Enterprise Associates, CVS Health Ventures, Lux Capital and Andreessen Horowitz.

  • Investor

    2022

  • Investor

    2022

Waltz Health is a digital health company that offers an AI-driven marketplaces for pharmaceutical supply chain.

Raised $55,500,000.00 from Define Ventures, Google Ventures, Twine Ventures, Echo Health Ventures, Byers Capital and The Blue Venture Fund.

  • Investor

    2021

  • Investor

    2021

Apella Technology is an AI startup that brings modern engineering to improve surgery.

Raised $24,000,000.00 from Twine Ventures, Upside Partnership, Casdin Capital, Vensana Capital, PFM Health Sciences and Operator Partners.

  • Investor

    2021

Teiko.bio is an immune profiling platform that enables clinicians to make informed decisions around patient response.

Raised $11,639,995.00 from Twine Ventures and Altitude Lab.

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