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Lucy Liu

Principal at Longwood Fund

Boston, Massachusetts

Overview 

Lucy Liu is a Principal at Longwood Fund in Boston, Massachusetts, with a background in neuroscience and genetics. She has held key roles at AAVantgarde Bio, Carbon Biosciences, and ImmuneID, showcasing her expertise in strategy, operations, and biochemistry. With a PhD in Neuroscience and Genetics from Baylor College of Medicine and experience at Harvard Medical School, Lucy Liu brings a strong research background to her current role at Longwood Fund, where she focuses on investing in early-stage biotech companies in the Boston/New England area.

Work Experience 

  • Principal

    2022 - Current

  • Senior Associate

    2020 - 2022

    Company creator + investor dedicated to helping transform innovative sciences into therapies for patients. - lead and support due diligence efforts for newco opportunities and syndicated investments. - founding head of strategy at ImmuneID. Supported and led series seed and A fundraise. - cofounder and founding VP of strategy and operations at Carbon Biosciences. Led series A fundraise. - board observer at Pulmocide.

Longwood Fund finances science-based companies that develop novel solutions for medical problems.

  • Board Observer

    2023

  • Board Observer

    2022

  • Co-Founder, Founding VP, Strategy & Operations

    2021 - 2022

    Carbon Biosciences is expanding the therapeutic potential of gene therapy through its proprietary platform which leverages novel parvoviruses that have been pressure tested by nature to target specific tissues and carry a larger cargo with minimal neutralizing immunity and the potential to re-dose. Founded by Longwood Fund and gene therapy pioneers, John F. Engelhardt, Ph.D., and Robert M. Kotin, Ph.D., Carbon is expanding the gene therapy toolbox for the treatment of the world’s most devastating and difficult to treat diseases. For more information, please visit our website www.carbonbio.com.

Carbon Biosciences is a biotech company that engages in the novel parvovirus gene therapy.

Raised $38,000,000.00 from Cystic Fibrosis Foundation, Longwood Fund, Astellas Venture Management, Solasta Ventures, Camford Capital, Agent Capital and UTokyo Innovation Platform.

  • Head of Strategy

    2020 - 2021

    Founded in late 2020, ImmuneID is a precision immunology Company that uses its genome-wide, high-throughput platform to provide a comprehensive understanding of individual immune responses. Based on technology developed by scientific founders Stephen Elledge (Harvard), Ben Larman (Johns Hopkins), and Tomasz Kula (Harvard), ImmuneID is employing a massively parallel, multiplexed, and unbiased systems to develop therapeutics for autoimmunity, severe allergy, oncology and infectious disease. Accomplishments: - Raised $50M series A with management team: led investor outreach and due diligence efforts - Acquired incubator lab space - Worked with management team to interview + hire R&D team - Led indication prioritization and strategy prior to CSO hire

  • Fellow

    2020 - 2020

    - Leverage scientific expertise to assist in metabolism focused newco formation with 4:59, 5AM’s internal newco formation initiative. - Assist in diligence for potential investment opportunities.

5AM Ventures is a venture capital firm that aims to finance seed and early-stage life sciences companies.

  • Damon Runyon Postdoctoral Fellow

    2017 - 2020

    Project – The fat-brain axis: identifying the roles of adipokine signaling in nervous system function. - Active contributor in an ongoing multi-institutional collaborative effort among world class scientists from HMS, MIT, Stanford, and USC. Publication in review. - Secured 4 years of research funding from the Damon Runyon Cancer Research Institute ($>250K)

  • Ph.D Candidate in Neuroscience

    2011 - 2017

    My thesis work revealed that lipid metabolic perturbations in the form of lipid droplet accumulations in glial cells (astrocytes and microglia) are a major contributing factor and a harbinger for Alzheimer's disease and neurodegeneration. These findings led to two first author manuscripts in Cell and Cell Metabolism with >900 citations. Accomplishments - Genetic Society of America Larry Sandler Memorial Award - 2018 - Harold Weintraub Graduate Student Award - 2017 - McKinsey: Houston Women Leaders Forum - 2016 - Scientific reviewer for Genetics and Scientific Reports

  • Researcher

    2009 - 2009

National Science Foundation is an independent federal agency that supports research and education in the fields of science and engineering.

  • Undergraduate Researcher

    2008 - 2008

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