MD

Marguerite Davis

Senior Clinical Data Analyst at Foresite Capital

Lewes, Delaware

Overview 

Marguerite Davis is a Senior Clinical Data Analyst at Foresite Capital, with a Ph.D. from the University of Delaware and experience in leading research projects at prestigious institutions like the University of Pennsylvania School of Medicine. She specializes in areas such as protein purification, immunoprecipitation, and cell culture, and has a strong background in biochemistry and molecular biology. Marguerite has held key roles such as Director of R&D Operations at Cabaletta Bio and Senior Project Manager in the Gene Therapy Program at the University of Pennsylvania School of Medicine, showcasing her expertise in managing complex research projects and driving innovation in the biotech and pharmaceutical sectors.

Work Experience 

  • Senior Clinical Data Analyst

    2024 - Current

    Identifying and tracking milestones and financial inflection points for portfolio companies and prospective investments, proactively monitor competitive intelligence, early adopter of prospective novel technology applications

  • Clinical Data Analyst

    2022 - 2024

Foresite Capital is a healthcare and life sciences investment firm.

  • Director R & D Operations

    2019 - 2022

Cabaletta Bio has adapted clinically-validated and FDA-approved CAR T cell technology to target B cell-mediated autoimmune diseases.

Raised $210,000,000.00 from Penn Medicine Co-Investment Program, Baker Brothers Advisors LLC, Deerfield Capital Management, 5AM Ventures, Redmile Group, Adage Capital Management, Boxer Capital and Cormorant Capital.

  • Senior Project Manager, Gene Therapy Program

    2017 - 2019

  • Project Manager, Gene Therapy Program

    2014 - 2017

  • Postdoctoral Research Associate, Translational Research on Pain Therapies

    2012 - 2014

    • Developed methods for therapeutic delivery of miRNAs and exosomes to animal models of pain • Authored a translational research study on changes in exosomal transcriptome in patients with complex regional pain syndrome (CRPS) and in animal models of inflammatory pain • Verified miRNA regulation of inflammatory mRNAs in vitro • Mentored undergraduate and graduate students, managed ordering and protocol development

  • Graduate Research Assistant, Biochemistry

    2007 - 2012

    The second half of my Ph.D. research focused on mechanisms of translational regulation and regeneration in adult rodent sensory neurons. I transitioned into the lab of Dr. Jeffery Twiss at Nemours/A.I. duPont Hospital, but kept my affiliation with University of Delaware's Chemistry and BIochemistry Department. • Quantified localization and colocalization between mRNA degradation proteins in rodent peripheral axons • Measured the half-life of localized axonal mRNAs in response to neurotrophic factors after axotomy

  • Graduate research assistant, Biochemistry

    2003 - 2007

    My graduate studies began in the lab of Dr. Mueller, who relocated his lab to University of Louisville in 2007. My initial training was in mechanistic enzymology and I developed a strong foundation in protein biochemistry. • Published the kinetic and spectrophotometric characterization of enzyme: fluorinated tRNA inhibitor adducts • Resolved a discrepancy between a radiometric and spectrophotometric measurement of a tritium-labeled RNA substrate that helped the lab perform experiments with an increased accuracy and incorporate quality control procedures

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