Marguerite Davis

Senior Clinical Data Analyst

2024 - Current

Identifying and tracking milestones and financial inflection points for portfolio companies and prospective investments, proactively monitor competitive intelligence, early adopter of prospective novel technology applications

Clinical Data Analyst

2022 - 2024

Director R & D Operations

2019 - 2022

Senior Project Manager, Gene Therapy Program

2017 - 2019

Project Manager, Gene Therapy Program

2014 - 2017

Postdoctoral Research Associate, Translational Research on Pain Therapies

2012 - 2014

• Developed methods for therapeutic delivery of miRNAs and exosomes to animal models of pain • Authored a translational research study on changes in exosomal transcriptome in patients with complex regional pain syndrome (CRPS) and in animal models of inflammatory pain • Verified miRNA regulation of inflammatory mRNAs in vitro • Mentored undergraduate and graduate students, managed ordering and protocol development

Graduate Research Assistant, Biochemistry

2007 - 2012

The second half of my Ph.D. research focused on mechanisms of translational regulation and regeneration in adult rodent sensory neurons. I transitioned into the lab of Dr. Jeffery Twiss at Nemours/A.I. duPont Hospital, but kept my affiliation with University of Delaware's Chemistry and BIochemistry Department. • Quantified localization and colocalization between mRNA degradation proteins in rodent peripheral axons • Measured the half-life of localized axonal mRNAs in response to neurotrophic factors after axotomy

Graduate research assistant, Biochemistry

2003 - 2007

My graduate studies began in the lab of Dr. Mueller, who relocated his lab to University of Louisville in 2007. My initial training was in mechanistic enzymology and I developed a strong foundation in protein biochemistry. • Published the kinetic and spectrophotometric characterization of enzyme: fluorinated tRNA inhibitor adducts • Resolved a discrepancy between a radiometric and spectrophotometric measurement of a tritium-labeled RNA substrate that helped the lab perform experiments with an increased accuracy and incorporate quality control procedures