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Nnamdi Okike

Managing Partner at 645 Ventures. Focused on investing in exceptional early

San Francisco, California

Overview 

Nnamdi Okike is the Managing Partner and Co-Founder at 645 Ventures, specializing in investing in early-stage software and software-enabled companies. He has successfully invested in companies like Cube Dev and RentSpree, showcasing a strong track record in identifying and supporting promising startups in sectors such as SMB Software and Social Commerce.

Work Experience 

  • Co-Founder and Managing Partner

    2013 - Current

    645 Ventures is an early-stage investment firm with over $550M AUM. We lead Seed and Series A rounds for software and software-enabled companies, and we work closely with exceptional teams to help them scale to the growth stage.

645 Ventures partners with exceptional founders at Seed and Series A to build iconic companies that scale to the growth stage.

  • Board Member

    2024

    Setpoint is a leading fintech that aims to streamline the hidden, cumbersome processes behind trillions in daily financial transactions. Backed by leading investors, Setpoint is pioneering the transformation of capital markets workflows from outdated manual systems to efficient, automated solutions, significantly reducing costs and enhancing speed for both borrowers and lenders. Founded in 2021, Setpoint’s capital and technology platform (Asset OS and Capital OS) enables auto, consumer, SMB, real estate and other asset-backed borrowers to grow profitably. Setpoint’s platform helps originators and lenders save time, reduce risk, and optimize for capital efficiency.

Setpoint.io develops a platform purpose-built for the future of asset-backed lending.

Raised $79,500,000.00 from Henry Kravis, Wells Fargo Strategic Capital, Outrunner Capital, Fifth Wall, Floating Point, Vesta Ventures, Citi Ventures, 75 & Sunny, Andreessen Horowitz and NextView Ventures.

  • Board Observer

    2024

    Cube is the universal semantic layer that makes it easy to connect BI silos, embed analytics, and power your data apps and AI with context.

Cube provides an analytical application platform to help companies manage and optimize their analytics workflow.

Raised $46,700,000.00 from Eniac Ventures, Bain Capital Ventures, Decibel Partners, Databricks Ventures and 645 Ventures.

  • Board Member

    2022

    The NVCA empowers the next generation of American companies that will fuel the economy of tomorrow.

National Venture Capital Association advocates for policies that promote long-term investment and encourage innovation.

  • Board Member

    2021

    Shift5 is the OT cybersecurity company that protects the world’s transportation infrastructure and weapons systems from cyberattacks.

Shift5 is a cybersecurity company that provides hardware and software solutions to defend operational technology (OT) platforms.

Raised $105,500,000.00 from Booz Allen Ventures, Moore Strategic Ventures, JetBlue Ventures, Teamworthy Ventures, Insight Partners, J. Hunt Holdings and General Advance.

  • Board Member

    2021

    Apty is a Digital Adoption Platform that helps enterprise optimize their business processes. Successful digital adoption involves both guiding people through new critical software applications and proactively pushing them to complete new processes. Only Apty combines the power of on-screen guidance with the time-saving automation of proactive process compliance. IT operation managers, Application Owners, VP HR/Sales, and leading CIOs alike all trust Apty to get the most out of their employees' use of web-based applications in their day-to-day job. Every month, nearly 1 million users use Apty to learn web-based apps and excel in their job in leading companies like Delta Airlines, Boeing, Agile CRM, and many more. Remember, the problem is not the software, it’s how you use it.

apty is a digital adoption platform that helps enterprises to optimize business processes.

Raised $12,900,000.00 from Companyon Ventures, 645 Ventures, Eudemian Ventures, Reformation Partners, Companyon Ventures and 645 Ventures.

  • Board Member

    2020

RentSpree provides software with a universal tenant screening process, renter management, partnership programs, and rental screening API.

Raised $27,720,000.00 from Venture MLS, California Association of Realtors, Gaingels, Rally Ventures, 645 Ventures, Green Visor Capital, KEC Ventures, Vesta Ventures and ECG-Research.

  • Board Member

    2019

Lunchbox Technologies is the premier online ordering system for enterprise restaurant chains to grow their online presence.

Raised $72,059,996.00 from Sweetgreen, DoorDash, 645 Ventures, Coatue, Beyond Capital, Apple Core Holdings, &pizza, Primary Venture Partners and Frontline Ventures.

  • Board Member

    2018

    Investor and board member of Negotiatus, a leading provider of SaaS e-procurement software for mid-market companies to large enterprises.

  • Member Of The Board Of Advisors

    2014 - 2017

    ALICE created the first complete communication, cost savings and revenue generation operations platform for hotels, which enhances the guest experience and connects all points within the hotel to simplify guest service - and make it more cost-effective. Expedia acquired a majority interest in ALICE in August 2017.

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