Sabrina Yang

Senior Principal

2017 - Current

Leading Flagship-founded bio platform companies from seed through Series B. Co-founded Empress Therapeutics and FL91 (now Ampersand Biomedicines) Leading entrepreneurial scientists in developing category-defining life sciences NewCo’s by exploring hundreds of venture ideas, conducting KOL calls, presenting company creation and investment plan to investment committee. Responsible for NewCo R&D strategy, business development, IP strategy, team formation, company milestones, platform proof points, developing budget, and interfacing with board members, scientific advisors, and consultants.

Chief Innovation Officer

2022

Leading platform innovation, corporate partnership, and external research collaboration

Co-Founder

2018

Co-Founder

2021 - 2023

FL91 is a Flagship founded platform company with the mission to make biologic drugs safer, based on a novel category of proteins that activate homeostasis-promoting pathways only at the disease site.

Translational Fellow

2016 - 2017

NSF Innovation Corps Translational Fellow: from research idea to commercialization. - Developed a small molecule T-cell targeting drug delivery platform for cancer immunotherapy - Project leader in the Biomed Entrepreneurship Course at the Broad Institute - Podium speaker at 2017 Immunotherapy of Cancer Conference (ITOC4) in Prague, Czech Republic - Selected participant in Harvard Healthcare Innovation and Commercialization semester-long course: start-ups, intellectual properties, venture capital, market analysis, investments, and pitch to VCs.

Venture Creation Fellow

2017 - 2017

Originate first-in-category platform technology ideas through effective analytical, communication and teamwork skills. Pitch company idea and plans to Flagship partners and CEO.

Doctoral Researcher

2011 - 2016

Laboratory of Dr. Darrell Irvine (HHMI investigator) at the Koch Institute of Integrative Cancer Research - Developed a strategy to enhance intracellular small molecule drug targeting to CD8+ T cells in vivo. Filed two patents. - Collaborated with computational scientists to understand the mechanisms of cell membrane penetration and fusion dynamics. - Podium Speaker at 2016 Keystone Symposium: Antibodies as Drugs and Cancer Vaccines, Whistler, Canada. - Poster presentation at 2015 Gordon Research Conference: Cancer Nanotechnology, Vermont. - Podium Speaker at 2014 BMES, San Antonio, Texas. - Silver Awards in MIT Materials Prototyping Contest (2013): Designed and built a solar-powered LED embedded in flexible material that lights up off-grid places.

Visiting Scholar

2014 - 2014

Researcher

2009 - 2009

Iron platinum nano alloy synthesis, characterization and applications in MRI/CT molecular contrast agents.