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Sridhar Ramaswamy

Venture Partner at GV

Boston, Massachusetts

Overview 

Sridhar Ramaswamy is a highly accomplished Physician based in Boston, Massachusetts, with expertise in diagnostics, company creation, and therapeutic invention, particularly in the fields of cancer, oncology, and drug development. He has held significant roles at institutions like TESARO, Inc., Harvard Medical School, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard, showcasing his leadership in healthcare, biotechnology, and genetics research. Ramaswamy's career highlights include serving as the Senior Vice President & Head of R&D at TESARO, Inc., and holding key positions at prestigious institutions like Harvard Medical School, demonstrating his strong background in leading research and development initiatives in the life sciences field.

Work Experience 

  • Venture Partner

    2021 - Current

    Investing in early-stage life science companies • Leyden Labs, Board Observer (2021-present) • Invetx, Board Observer (2022-24 / M&A 2024) • Invivyd, Board Observer (2020-21 / IPO 2021)

  • Entrepreneur In Residence

    2019

    Biotech company creation • Q1, Inc., Founder & CEO (2020-present) • Q2, Inc., Founder & CEO (2023-present)

  • Guest Lecturer

    2019

    • Massachusetts Institute of Technology • Broad Institute of Harvard & MIT • Harvard Business School

Google Ventures is an investment arm of Alphabet that provides seed, venture, and growth-stage funding to technology companies.

  • Senior Vice President & Head, R&D

    2016 - 2019

    Research & Development, Cancer Therapeutics, Executive Leadership • Built and led a matrix team of 70 drug discovery, translational, and development experts that worked closely with BD, CMC, medical, regulatory, and commercial strategy groups to enable the integrated and externalized discovery, development, and commercialization of a cancer and immuno-oncology pipeline • Directed early pipeline creation through discovery, acquisition, and partnership; early development of new therapeutics from concept through first-in-man studies; and translational science to best position our drugs at the right dose, schedule, and cancer indications so patients most likely benefit • Contributed to small-molecule and antibody discovery, early development, translational biomarker identification & strategy, clinical development & regulatory approval, and commercialization of 11 cancer drugs including niraparib (PARP1/2), dostarlimab (PD1), cobolimab (TIM3), and rolapitant (NK1) for patients with ovarian, prostate, uterine, rectal and other solid tumors • Represented R&D externally with the scientific, medical, regulatory, commercial, and investor communities • Served as a key member of the executive leadership team that led TESARO as a publicly traded, oncology-focused, global biopharmaceutical company and spearheaded its successful acquisition and integration by GSK for $5.1B

TESARO is an oncology-focused biopharmaceutical company identifying better cancer therapies to improve the lives of patients with cancer.

Raised $1,095,699,915.00 from Ally Bridge Group, Johnson & Johnson, InterWest Partners, New Enterprise Associates, Kleiner Perkins and Future Fund.

  • Associate Professor of Medicine

    2001 - 2019

    Medical Oncology & Hematology, Translational & Basic Research, Teaching & Administration • Directed the highly-specialized, multidisciplinary care for patients with breast, GI, and hematologic cancers in both the inpatient and outpatient settings at the Massachusetts General Hospital, Brigham & Women's Hospital, and Dana-Farber Cancer Institute • Founded and directed a highly-influential, NIH-funded, multidisciplinary research program focused on understanding how human carcinomas grow and progress from localized cancers, via circulating tumors cells, into advanced, metastatic, dormant, and treatment-resistant disease (h-index = 73) • Developed cancer systems biology approaches to study human tumors as complex, adaptive, multi-scale systems • Disseminated many tools, methods, and approaches invented by my research group to the worldwide cancer research, translational medicine, and drug development communities • Taught a generation of medical & graduate students, interns & residents, and clinical & research fellows in the classroom, at the bench, and the bedside.

  • MGH / Samana Cay Endowed Investigator

    2015 - 2017

    Cancer Biology & Therapeutics, Translational & Basic Research, Teaching, Administration

  • Director, Center for Computational Biology

    2004 - 2017

    Integrative, Systems, & Computational Biology, Bioinformatics, Data Science

  • Tucker Gosnell Investigator

    2004 - 2017

    Medical Oncology, Cancer Biology & Therapeutics, Translational & Basic Research, Teaching, Administration

  • Principal Investigator, Center for Cancer Research

    2004 - 2017

    Patient-oriented laboratory research

  • Attending Physician in Medicine & Cancer Center

    2000 - 2017

    Medical Oncology, Hematology, Internal Medicine

  • Associate Member

    2006 - 2017

    Genetics & Genomics, Systems Biology, Data Science

  • Principal Member

    2006 - 2017

    Stem Cell Biology, Regenerative Medicine

Harvard Stem Cell Institute is a a community of scientists in stem cell science seeking to bring new treatments and new life to patients.

  • Associate Member

    2006 - 2017

    Cancer Biology, Cancer Therapeutics & Diagnostics

Ludwig Cancer Research is a global community of leading scientists pursuing innovative ways to prevent and control cancer.

  • Attending Physician in Medicine

    2001 - 2004

    Medical Oncology, Therapeutics, & Diagnostics, Translational & Basic Research, Cancer Biology, Teaching

Dana-Farber Cancer Institute is a center dedicated to carrying out adult and pediatric cancer treatment activities and advanced research.

Raised $67,079,019.00 from Llama, Hyundai Hope On Wheels, Hyundai Hope On Wheels, Break Through Cancer, Paula and Rodger Riney Foundation, Massachusetts Life Sciences Center and Massachusetts Life Sciences Center.

  • Attending Physician in Medicine

    2001 - 2004

    Medical Oncology, Therapeutics, & Diagnostics, Translational & Basic Research, Cancer Biology, Teaching

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